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In trials with multiple intervention arms

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pandora charms In the earlier trial we had to exclude many, otherwise eligible, participants because an altered mental state prevented them from giving informed consent. For the current trial we sought permission from the hospitals’ human research ethics committee for the next of kin to sign for patients who were unable to consent themselves.Intervention, allocation concealment, and maskingWe randomised patients either to routine care (control group), with catheters scheduled to be replaced every three days according to hospital policy, or to a group where the peripheral intravenous catheter was not replaced unless there was a clinical indication (clinically indicated group). Irrespective of the assignment pandora canada, a decision to change a catheter at any time because of clinical indications such as phlebitis, infiltration, or unexplained fever could be implemented. pandora charms

pandora jewelry For meta analysis of rare events, we reported odds ratios using Peto’s exact method and calculated 95% confidence intervals with a fixed effect model using RevMan 5.3.31 32 All post randomisation events were included, so when data from the lead out and post treatment phases were available, we combined them with the data from the randomised phase. In trials with multiple intervention arms, we added the data on arms arithmetically to get a combined drug arm. Of the remaining 73 clinical study reports, we excluded five that had no patient narratives or individual patient listings of adverse events. pandora jewelry

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